脑损伤具有高致残率和死亡率,主要原因为脑损伤后继发性脑损伤。继发性脑损伤可由脑灌注压不足、脑组织氧代谢障碍、脑内过度炎性反应、受损脑组织对继发性损伤的敏感性增强、脑损伤后致伤因子的释放增加等多种原因引起,可通过不同途径加重脑损伤后的病理生理改变,其实质是脑组 Brain damage with high morbidity and mortality, mainly due to secondary brain injury after brain injury. Secondary brain injury may be caused by insufficient cerebral perfusion pressure, oxygen metabolism disorders of the brain, excessive inflammatory reaction in the brain, impaired brain tissue sensitivity to secondary injury, increased release of injury agents after brain injury and many other Cause, can be increased by different pathophysiological changes after brain injury, its essence is the brain group