目的探讨盐酸哌唑嗪（ＰＺ）点眼对葡萄膜巩膜房水流出量的影响。方法用示踪剂异硫氰酸荧光素牛血清白蛋白（ＦＩＴＣＢＳＡ）对兔眼进行前房灌注，测定对照组和ＰＺ点眼组双眼前葡萄膜、前巩膜、后葡萄膜、后巩膜、视网膜和残余液体的前房水再现量，计算葡萄膜巩膜流出量。结果ＰＺ组双眼葡萄膜巩膜流出量显著高于对照组，ＰＺ点眼侧显著高于对侧眼。对照组和ＰＺ组双眼的前房水再现量均以前葡萄膜、前巩膜和残余液体为多。结论家兔ＰＺ点眼后增加葡萄膜巩膜途径房水流出量，房水主要由前巩膜排出。科 Objective To investigate the influence of prazosin hydrochloride (PZ) on the outflow of aqueous humor of the uveal sclera. Methods Anterior chamber perfusion was performed with fluorescein isothiocyanate-bovine serum albumin (FITCBSA) in traumatic eyes. The anterior uveal, anterior sclera, posterior uveal, posterior sclera, Retinal and residual fluid anterior chamber water reproduction amount calculated uveal scleral outflow. Results The eyelid scleral outflow in both eyes of PZ group was significantly higher than that of the control group, and the eye side of PZ was significantly higher than that of the contralateral eye. In the control and PZ groups, both anterior and posterior aqueous rehydration volumes in the eyes were greater than in the pre-uveal, anterior sclera and residual fluid. Conclusion Rabbit PZ after eyes increased aqueous humor outflow of aqueous humor, aqueous humor mainly from the anterior sclera. Section