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促胰岛细胞再生和增殖的RegⅢ是调控病理生理机能的重要多功能因子，具有参与炎症、肿瘤调控和促增殖效应.RegⅢ可与IL-6/JAK2/STAT3信号通路形成调节回路.目前普遍认为，炎症微环境中持续分泌IL-6在促进胰腺细胞增殖和恶性转化中发挥重要作用.
Reg3g促胰腺癌发生的免疫学调控机制研究
【摘 要】
：
促胰岛细胞再生和增殖的RegⅢ是调控病理生理机能的重要多功能因子，具有参与炎症、肿瘤调控和促增殖效应.RegⅢ可与IL-6/JAK2/STAT3信号通路形成调节回路.目前普遍认为，炎症微环境中持续分泌IL-6在促进胰腺细胞增殖和恶性转化中发挥重要作用.
【机 构】
：
华中科技大学同济医学院药学院药理室 中国
【出 处】
：
2016第九届世界癌症大会
【发表日期】
：
2016年7期
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