C-Type Natriuretic Peptide plays a crucial role in regulation of ovulation in Polycystic ovary syndr

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户:josenhu
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Polycystic ovary syndrome(PCOS)is a complex endocrinopathy which affects 5%-7%of reproductive-age womens fertility.However,the specific causes of anovulation are still not well clarified.Natriuretic peptide type C/natriuretic peptide receptor 2(NPPC/NPR2)system is essential for sustaining oocyte meiotic arrest until preovulatory luteinizing hormone(LH)surge decreases NPPC/NPR2 levels and triggers meiotic resumption.
其他文献
Objective: analyzing the proteins in exosomes isolated from blood of hypertension patients to explore potential role of exosomic factors in hypertension.Method: forty-seven patients and healthy subjec
atherosclerosis primarily involved systemic arteries.Luminal surface,a monolayer of endothelial cells,of artery directly exposes to blood and is susceptible to active substances in the blood.Exosomes
Organophosphorus compounds are widely present in the environment since its wide application,which exhibit serious impact on organisms.This study is mainly to explore the effects of paraoxon on atrial
Cardiac hypertrophy is an adaptive response to the biomechanical stress,but it is the early event to induce cardiomyocyte apoptosis and lead to heart failure.Sialylation is upregulated during cardiac
Background and purpose: Vascular endothelial cells are activated in response to a variety of pathological insults,such as oxidative stress,mechanical stress,and elevated autocrine-paracrine mediators(
Background: Brugada syndrome(BrS)is an inherited cardiac condition characterized by signature changes in the electrocardiogram(ECG)and risk of arrhythmic sudden death.Here we used patient-derived card
Background: Adipose-derived adipokiens are documented to be associated with development of various heart failures through chronic inflammation and cardiac cell apoptosis.Omentin is a novel adipokine a
Transplantation of hormone producing cells is an experimental endocrine dysfunction treatment.The present study investigated the effects of orchidectomy and transplantation of interstitial cell suspen
Natriuretic peptide type C(NPPC)activation of the guanylyl cyclase-linked natriuretic peptide receptor 2(NPR2)maintains oocyte meiotic arrest.Luteinizing hormone(LH)-dependent epidermal growth factor(
pH regulation affects a series of processes during mammalian reproduction,such as sperm capacitation,fertilization,embryo implantation,and early development.The uterine fluid is rich in HCO3 –.During