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目的 :观察利多卡因静注治疗眩晕症即时及远期的临床效果。方法 :随机将1 0 8例眩晕症患者分为治疗组 60例 ,对照组 48例 ,均于发病 2 4 h内治疗。对照组采用低分子右旋糖酐 5 0 0 ml,复方丹参注射液 30 ml静脉滴注 ,每日 1次 ;治疗组在对照组的基础上加用 1 0 0 mg利多卡因 ,稀释于 1 0 %葡萄糖 45 ml内 ,以 3ml/min的速度缓慢静推 ,每日 1次 ,两组均连用 2个疗程 ,观察治疗后 4h及 2 4 h的即时及 1 0 d长期疗效。结果 :治疗组远期治愈率、总有效率均高于对照组 ,且短时有效率远远高于对照组 ,有统计学意义 ( P<0 .0 5 )。结论 :利多卡因联合低分子右旋糖酐及复方丹参注射液治疗眩晕症有良好的远期临床疗效和短时症状缓解疗效 ,值得进一步临床应用及研究。
Objective: To observe the immediate and long-term clinical effects of intravenous injection of lidocaine for vertigo. Methods: One hundred and eight patients with vertigo were randomly divided into treatment group (60 cases) and control group (48 cases), all of which were treated within 24 hours. The control group received low molecular weight dextran (500 ml) and compound Danshen injection (30 ml) intravenously once daily. The treatment group was given 100 mg lidocaine on the basis of the control group, diluted in 10% glucose 45ml, 3ml / min slow intravenous push, once daily, two groups were treated with two courses, observed 4h and 24h after treatment and 10d long-term efficacy. Results: The long-term cure rate and total effective rate of the treatment group were higher than that of the control group, and the short-term efficiency was much higher than that of the control group (P <0.05). Conclusion: Lidocaine combined with low molecular weight dextran and compound Danshen injection in the treatment of vertigo has good long-term clinical efficacy and short-term symptom relief efficacy, worthy of further clinical application and research.