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目的:评价急性脊髓炎(AM)的药物疗效。方法:回顾分析45例AM患者的临床表现,按皮质激素开始运用的时间、剂量及合用甘露醇否分组进行疗效对照。结果:①发病2周内应用足量激素者,治愈率明显优于发病后3周才应用者。②急性期并用甘露醇者,疗效亦优于未用者。③对于重症AM,MRI显示脊髓明显肿胀者,超大剂量激素疗效优于常规剂量者。结论:激素早期、足量、必要时超大剂量运用并配合甘露醇治疗,可提高AM的疗效。
Objective: To evaluate the drug efficacy of acute myelitis (AM). Methods: A retrospective analysis of 45 cases of AM patients with clinical manifestations, according to the start of corticosteroids time, dosage and combined with no effect of mannitol group control. Results: ① The application of adequate hormone within 2 weeks of onset, the cure rate was significantly better than 3 weeks after the onset of application only. ② acute phase with mannitol, the effect is also better than the unused. ③ For severe AM, MRI showed significant swelling of the spinal cord, the effect of large doses of hormones than conventional dose. Conclusion: Early, adequate hormones, if necessary, use of large doses and with mannitol, can improve the efficacy of AM.