Azithromycin是一种大环内酯类新型广谱抗生素,化学结构与红霉素相似,但由于大环内酯环的N上连有甲基,从而增加了对酸的稳定性。研究表明,Azithromycin在肺组织中有很高的浓度。为了进一步证明该药治疗下呼吸道感染的效果,26个医疗中心使用了Azithromycin并与头孢克罗做了对照。共有546名急性支气管炎和肺炎病人接受治疗,资料完整能够评价疗效的病人是 Azithromycin is a new macrolide broad-spectrum antibiotic with a similar chemical structure to erythromycin but its stability to acids is increased due to the methyl group attached to the N of the macrolide ring. Studies have shown that Azithromycin has a high concentration in lung tissue. To further demonstrate the drug’s efficacy in treating lower respiratory infections, Azithromycin was used in 26 centers and compared with cefaclor. A total of 546 patients with acute bronchitis and pneumonia were treated, the data is complete to evaluate the efficacy of the patient