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目的评价国产压力传感器心导管、电磁流量传感器心导管行＋ＧＺ负荷下心血管腔内压、血流量测定的可行性，并观察＋ＧＺ负荷下血液动力学变化规律。方法９只麻醉犬暴露于＋１ＧＺ、＋３ＧＺ、＋５ＧＺ、＋７ＧＺ、＋９ＧＺ负荷各９０ｓ，监测左室腔内压（ＰＬＶ）、胸主动脉腔内压（ＰＴ）、髂动脉腔内压（ＰＣ），颈动脉每搏血流量（ＣＡＢＦ）、心阻抗图（ΔＺ）、心阻抗微分图（ｄｚ／ｄｔ）和心电图（ＥＣＧ）。结果①国产压力传感器心导管和电磁流量传感器可实时记录＋ＧＺ负荷下压力、血流量变化；ΔＺ、ｄｚ／ｄｔ图形变化紊乱，难以进行心功能定量分析；②ＧＺ负荷下犬左心室与大动脉腔内压和ＣＡＢＦ减低速率随＋ＧＺ值增大而增快。ＣＡＢＦ终断时心电图示ＱＲＳ主波向下。结论可以用国产压力传感器心导管行＋ＧＺ负荷下血液动力学监测。高＋ＧＺ负荷下注意ＱＲＳ主波方向，尽早采用抗荷措施。
Objective To evaluate the feasibility of measuring intracardiac pressure and blood flow in patients undergoing cardiac catheterization and magnetic flow sensor cardiac catheterization under the condition of + GZ load, and observe the changes of hemodynamics under + GZ stress. Methods Nine anesthetized dogs were exposed to + 1GZ, +3 GZ, +5 GZ, +7 GZ, and +9 GZ for 90s respectively. The left ventricular pressure (PLV), thoracic aortic lumen pressure (PT), iliac artery pressure Arterial stroke volume (CABF), cardiac impedance (ΔZ), cardiac impedance derivative (dz / dt), and electrocardiogram (ECG). Results ① Domestic catheter and electromagnetic flow sensor can record pressure and blood flow under the + GZ load in real time. The changes of ΔZ and dz / dt patterns are difficult to quantify. It is difficult to quantify heart function under the GZ load. And CABF decrease rate increases with the increase of + GZ value. ECG at the end of CABF ECG QRS main wave down. CONCLUSIONS: Home-made pressure sensors can be used for cardiac catheterization and hemodynamic monitoring under GZ stress. Pay attention to QRS main wave direction under high + GZ load and adopt anti-load measures as soon as possible.