论文部分内容阅读
目的:评价微创介入方法提高脓腔内化疗药物浓度治疗脊柱结核脓肿的疗效。方法:回顾性分析我院2015年01月至2015年12月间50例脊柱结核合并脓肿患者,CT或MRI及病灶活检证实为脊柱结核,不伴严重后凸畸形、严重椎体不稳及截瘫,在全身化疗的同时,行CT引导下经皮微创穿刺引流术,术后置管持续灌注冲洗,提高局部抗结核化疗药物浓度治疗脊柱结核脓肿。结果:全组病例病灶清除及置管顺利,局部化疗时间45±21d,随访12±6个月,患者的症状和脓肿消失,无严重并发症发生,所有患者均恢复正常工作或生活。结论:微创介入方法提高脓腔内化疗药物浓度治疗脊柱结核脓肿,是一种简便安全,并发症少,临床疗效较好的微创治疗手段。
OBJECTIVE: To evaluate the efficacy of minimally invasive intervention to increase the concentration of chemotherapeutic drugs in the treatment of spinal tuberculosis abscess. Methods: A retrospective analysis of 50 patients with spinal tuberculosis complicated with abscess from January 2015 to December 2015 in our hospital was performed. CT or MRI and biopsy confirmed spinal tuberculosis without severe kyphotic deformity, severe vertebral instability and paraplegia At the same time of systemic chemotherapy, CT-guided percutaneous minimally invasive puncture drainage, continuous perfusion irrigation after catheterization to improve the local anti-TB chemotherapy drug concentration in the treatment of spinal tuberculosis abscess. Results: All cases were successfully cleared and catheterized. The local chemotherapy time was 45 ± 21 days. The patients were followed up for 12 ± 6 months. The symptoms and abscess disappeared and no serious complications occurred. All patients returned to normal work or life. Conclusion: The minimally invasive interventional method to increase the concentration of chemotherapy drugs in the abscess cavity for the treatment of spinal tuberculosis abscess is a minimally invasive and safe treatment method with less complications and better clinical curative effect.