暴发性紫癫是一种急性综合征,有迅速发展的播散性紫癜,伴有血管性虚脱和低血压性休克。这种疾病为细菌性脓毒病,少见的并发症,多发生于儿童,最多见的是脑膜炎球菌菌血症。亦有报告有拖延的暴发性紫癜而不伴有脓毒病,可能与原来所患病毒或细菌性疾病有关。1984年底,在巴西圣保罗州一个小镇名普罗米桑(Promissao)有10名儿童患暴发性紫癜死亡,患儿4男6女,发热后12～42小时出现淤斑伴有低血压休克,死时出现明显紫癜,最多见是在面部及四肢, Epilepsy is an acute syndrome of epilepsy, the rapid development of disseminated purpura, accompanied by vascular collapse and hypotension shock. The disease is bacterial sepsis, a rare complication occurring mostly in children, the most common being meningococcal bacteremia. There are also reports of prolonged purpura fulminans without sepsis, may be related to the original virus or bacterial disease. At the end of 1984, 10 children with fulminant purpura died of purpura purpura in a small town in the state of Sao Paulo, Brazil. They were 4 males and 6 females and developed ecchymosis and hypotension shock 12 to 42 hours after fever Purpura when obvious, the most common is the face and limbs,