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目的探讨奥拉西坦联合马来酸桂哌齐特治疗老年脑梗死的临床价值。方法选取在赣州市立医院接受治疗的100例老年脑梗死患者进行研究,随机将其均分为对照组和实验组(n=50)。对照组接受马来酸桂哌齐特240mg静脉滴注治疗,为期15d,实验组在此基础上接受奥拉西坦4g静脉滴注治疗,为期10d,对比分析2组患者临床治疗效果。结果实验组的治疗总有效例数35例,高于对照组的治疗总有效例数25例,差异有统计学意义(P<0.05)。结论由本研究结果可知,奥拉西坦联合马来酸桂哌齐特是一种较为有效的老年脑梗死临床治疗药物,能够有效改善脑代谢能力和脑组织微循环状态,延长血管的扩张时间,改进脑血管强度,保护脑细胞,增强脑细胞的抗缺氧缺血能力。
Objective To investigate the clinical value of oxiracetam combined with cinepazide maleate in the treatment of senile cerebral infarction. Methods 100 elderly patients with cerebral infarction who were treated in Ganzhou Municipal Hospital were randomly divided into control group and experimental group (n = 50). The control group received 240 mg of cinepazide maleate intravenously for 15 days. On the basis of this, the experimental group received 4 mg of oxiracetam intravenously for a period of 10 days. The clinical effects of the two groups were compared. Results In the experimental group, the total effective cases were 35 cases, which was higher than that of the control group (25 cases). The difference was statistically significant (P <0.05). Conclusions From the results of this study, oxiracetam combined with cinepazide maleate is a more effective clinical treatment of senile cerebral infarction, can effectively improve brain metabolism and brain microcirculation, extend the time of vascular expansion, Improve the strength of cerebral blood vessels, protect brain cells and enhance brain cells against hypoxia-ischemia.