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在适当剂量强噪声暴露后,豚鼠听皮层由较强短声诱发的电位振幅可以增大。脉冲噪声峰值150dB脉宽50ms100—500次,或146dB脉宽10ms2000次,或持续白噪声105dB15min,可使暴露后的最大电位比暴露前的增大30—120%,其潜伏期平均约延长15%,5—20min内的暂时性阈移为16—48dB。过大的暴露剂量则使电位变小。在皮层诱发电位增大的同时,耳蜗电位、内膝体及小脑诱发电位均不增大。皮层电位的增大现象不受麻醉、掩蔽及皮层表面放置马钱子素的影响。
After exposure to a moderate dose of strong noise, the amplitude of the potential induced by stronger short beacons in the auditory cortex of guinea pigs may increase. Pulse peak 150dB pulse width 50ms100-500 times, or 146dB pulse width 10ms2000 times, or continuous white noise 105dB15min, the maximum potential after exposure than before exposure increased by 30-120%, the average latency of about 15% The temporary threshold shift within 5-20 min is 16-48 dB. Excessive exposure dose decreases potential. Cortical evoked potentials increased at the same time, the cochlear potential, the inner knee and cerebellar evoked potentials were not increased. The increase in cortical potential is not affected by anesthesia, masking and strychnine placement on the surface of the cortex.