蛇根木细胞悬浮培养进行紫杉醇的生物转化

来源 :植物学报 | 被引量 : 0次 | 上传用户：jsjyao

【摘要】

：

通过理化及光谱学方法,从蛇根木(Rautwolfia serpentina(L.)Benth.et Kurz.)悬浮细胞内分离到3个紫杉醇同系物,高分辨1H-NMR和MS结构分析表明,它们分别为10-脱乙酰紫杉醇、ba

【作者】

：

赵昱于荣敏 Cornelia SCHROEDER Ian

【机构】

：

浙江大学药学院,Lehrstuhl fiir Pharmazeutische Biologie,暨南大学药学院,Cornelia SCHROEDER,Department of Chemistry

【出处】

：

植物学报

【发表日期】

：

2004年期

【关键词】

：

生物转化蛇根木细胞培养紫杉醇紫杉烷类 biotransformation cell culture Paclitaxel taxanes Rauwolf

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通过理化及光谱学方法,从蛇根木(Rautwolfia serpentina(L.)Benth.et Kurz.)悬浮细胞内分离到3个紫杉醇同系物,高分辨1H-NMR和MS结构分析表明,它们分别为10-脱乙酰紫杉醇、baccatinⅢ和10-deacetylbaccatinⅢ.本实验未检测出紫杉醇的苷化或羟基化衍生物.

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蛇根木细胞悬浮培养进行紫杉醇的生物转化

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