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目的 采用放射性核素胃食管显像评价新生儿胃排空和胃食管反流情况。方法 77例处于疾病恢复期的新生儿患者 ,其中足月儿 46例、早产儿 31例。用胃食管显像测定 6 0min胃排空率 (GE6 0 % )和胃食管反流指数 (RI)。结果 所有患儿均未发现不良反应。早产儿的胃排空率 [(2 8 3± 7 7) % ]明显低于足月儿 [(4 9 2± 12 8) % ],P <0 0 0 1。胎龄与胃排空率间存在正相关关系。足月儿无症状反流率为 6 0 9% (2 8 46例 ) ,早产儿中高达 83 9% (2 6 31例 ) ,差异有显著性 (P <0 0 5 )。结论 胃食管显像检测新生儿胃排空和胃食管反流是可行的 ;早产儿的胃排空率低于足月儿 ,正常新生儿中存在一定比例的无症状胃食管反流
Objective To evaluate the effects of radionuclide gastro-esophageal imaging on neonatal gastric emptying and gastroesophageal reflux disease. Methods A total of 77 neonates with convalescent disease were enrolled, including 46 full-term infants and 31 preterm infants. The gastric emptying rate (GE6 0%) and the gastroesophageal reflux index (RI) at 60 min were determined by gastroscopy. Results No adverse reaction was found in all children. The rate of gastric emptying in preterm infants was significantly lower than that in term infants (492 ± 12 8%) (P <0.01). There was a positive correlation between gestational age and gastric emptying rate. The rate of asymptomatic reflux in term infants was 69.9% (2846 cases), and 83.9% (2631 cases) of preterm infants with a significant difference (P <0.05). Conclusion Gastro-esophageal imaging in detecting neonatal gastric emptying and gastroesophageal reflux is feasible. The rate of gastric emptying in premature infants is lower than that in term infants. There is a certain proportion of asymptomatic gastroesophageal reflux in normal neonates