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通过小鼠模型研究机体对申克孢子丝菌的防御机理。正常小鼠在接种申克孢子丝菌后 ,伴随着 PMNs的浸润 ,真菌发生裂解并逐渐消失 ;而裸鼠接种菌体后 ,在早期防御过程中因 PMNs杀伤活性的缺乏导致真菌繁殖扩散 ,直至动物死亡。
The Mechanism of Defensive Mechanism of Sporotrichenosum against Schenckiser Disease by the Mouse Model. After inoculation of Sporotrichosis, the normal mice were lysed by PMNs and the fungi lysed and gradually disappeared. However, the inactivation of PMNs during the early defensive phase caused the propagation of fungi to proliferate in nude mice Animal death.