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全反式维甲酸可使约 85 %急性早幼粒细胞白血病获得缓解[1] 。维甲酸在治疗上存在维甲酸耐药的缺陷 ,对维甲酸耐药患者即使缓解也在短期内复发 ,并且再用维甲酸治疗无效。为了进一步探讨新的治疗方法 ,我们自 1992年 10月～1999年 12月用三氧化二砷 (Ａｓ2 Ｏ3 )静脉滴注治疗 1
All-trans retinoic acid can relieve about 85% of acute promyelocytic leukemia [1]. Retinoic acid has a defect in the treatment of retinoic acid resistance. Retinoic acid resistant patients will relapse in the short term even if they are relieved, and retinoids treatment will not be effective. In order to further explore new therapeutic methods, we have treated with As2O3 intravenously from October 1992 to December 1999 1