目的探讨急性心肌梗死(AMI)患者血糖水平与经皮冠状动脉介入(PCI)干预后住院期间心脏不良事件的相关性。方法入选312例初发 AMI 患者于入院即刻测定静脉血糖,并于发病24 h 内行急诊 PCI。根据入院即刻血糖水平分为高血糖组(血糖>11 mmol/L,44例)和血糖正常组(血糖≤11 mmol/L,268例);按是否合并糖尿病分为糖尿病组(81例)和非糖尿病组(231例)。随访患者住院期间病死率及术后180 d 心脏不良事件发生率。结果无论是否合并糖尿病,高血糖组住院期间病死率及 PCI 术后180 d 心脏不良事件发生率均明显高于血糖正常组(18.2%比3.0%,P<0.001;25%比12.7%,P=0.047),多因素分析显示入院即刻血糖为死亡及心脏不良事件的独立预测因素(OR 5.15,95% CI 1.74～15.28,P=0.003及 OR 2.84,95% CI 1.18～6.83,P=0.019),而是否合并糖尿病对上述终点无明显影响。结论无论是否合并糖尿病,入院即刻高血糖是 AMI 患者 PCI术后住院期间病死率和180 d 心脏不良事件的相对独立危险因素。 Objective To investigate the relationship between the blood glucose level in patients with acute myocardial infarction (AMI) and cardiac events during hospitalization after percutaneous coronary intervention (PCI). Methods A total of 312 patients with AMI were enrolled in the study. Venous blood glucose was measured immediately after admission and emergency PCI was performed within 24 hours. According to the instant blood glucose level at admission, the subjects were divided into hyperglycemia group (blood glucose> 11 mmol / L, 44 cases) and normal blood glucose group (blood glucose <11 mmol / L, 268 cases) Non-diabetic group (231 cases). The patient mortality during hospitalization and the incidence of adverse cardiac events 180 days after operation were followed up. Results The incidence of hospital mortality and high incidence of adverse cardiac events 180 days after PCI in hyperglycemia group were significantly higher than those in normal glucose group (18.2% vs 3.0%, P <0.001; 25% vs 12.7%, P = 0.047). Multivariate analysis showed that immediate blood glucose at admission was an independent predictor of death and adverse cardiac events (OR 5.15, 95% CI 1.74-15.28, P = 0.003 and OR 2.84, 95% CI 1.18-6.33, P = 0.019) Whether or not diabetes mellitus had no significant effect on the above endpoints. Conclusions Immediate hyperglycemia at admission is a relatively independent risk factor for mortality in hospitalized patients with AMI and 180-day adverse cardiac events in AMI patients with or without diabetes mellitus.