论文部分内容阅读
冠心病的遗传因素研究是发病机制研究的重要组成部分,全基因组关联研究策略的发展使得其在探究冠心病的遗传因素及发病机制上具有巨大的价值,随着流行病学的进一步发展及应用,将遗传学和流行病学的研究设计方法相结合,已成为目前全基因组关联研究策略的重要方法。在此对近年国内外该方面的研究进展进行归纳总结,探讨存在的问题,并对未来发展趋势作一展望。
The study of genetic factors of coronary heart disease is an important part of the pathogenesis research. The development of genome-wide association research strategy makes it have great value in exploring the genetic factors and pathogenesis of coronary heart disease. With the further development of epidemiology and its application The combination of genetics and epidemiological research design methods has become an important method for genome-wide association research. This article summarizes the research progress in recent years at home and abroad in this area, discusses the existing problems and looks forward to the future development trend.