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目的探讨蒙脱石散与妈咪爱序贯治疗对新生儿高胆红素血症的影响。方法将足月新生儿高胆红素血症患儿,按入院时间先后随机分为常规治疗的A组、蒙脱石散+妈咪爱同时治疗的B组、蒙脱石散+妈咪爱序贯治疗的C组,比较分析3组患儿胆红素水平的变化和黄疸退尽时间。结果治疗后每日胆红素平均下降数值方面:C组为(69.33±22.51)umol/L,B组为(49.02±20.32)umol/L,A组为(38.89±18.46)umol/L,各组间存在显著性差异。黄疸退尽平均时间方面:C组为(4.01±1.86)d,B组为(5.09±2.12)d,A组为(6.18±2.57)d,各组间存在显著性差异。结论先用蒙脱石散吸除胆红素等有害物质,再用妈咪爱恢复肠道功能是治疗新生儿高胆红素血症时较好的用药顺序和方法,值得临床推广应用。
Objective To investigate the effects of montmorillonite powder and Mommy’s love sequential therapy on neonatal hyperbilirubinemia. Methods The full-term neonates with hyperbilirubinaemia were randomly divided into group A, treatment group A, treatment group B, montmorillonite + mommy love Sequential treatment of C group, a comparative analysis of three groups of children with changes in bilirubin levels and jaundice withdrawal time. Results After treatment, the average daily bilirubin value decreased: (69.33 ± 22.51) umol / L in group C, (49.02 ± 20.32) umol / L in group C and (38.89 ± 18.46) umol / L in group A There were significant differences between groups. The average duration of jaundice withdrawal was (4.01 ± 1.86) days in group C, (5.09 ± 2.12) days in group B and (6.18 ± 2.57) days in group A, with significant differences among the groups. Conclusions The first use of montmorillonite powder to absorb bilirubin and other harmful substances, and then mommy love to restore intestinal function is the treatment of neonatal hyperbilirubinemia better medication sequence and method, worthy of clinical application.