依曲韦林(etravirine,1),化学名为4-[[6-氨基-5-溴-2-[(4-氰基苯基)氨基]嘧啶-4-基]-氧基]-3,5-二甲基苄腈,是强生公司下属Tibotec公司开发的新一代非核苷类逆转录酶抑制剂(NNRTIs),2008年1月经美国FDA批准上市,成为高效抗逆转录病毒治疗(HAART)药物的重要组 Etravirine (1) has the chemical name 4 - [[6-amino-5-bromo- 2 - [(4- cyanophenyl) amino] pyrimidin- 4-yl] -oxy] -3 , 5-dimethylbenzonitrile, is a new generation of non-nucleoside reverse transcriptase inhibitors (NNRTIs) developed by Johnson & Johnson’s Tibotec company. It was approved by the FDA in January 2008 and became an effective antiretroviral therapy (HAART) Important group of drugs