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The distribution of mitomycin(MIT) for injection in aqueous surfactant two phases(ASTP), consisted of cetyltrimethylammonium bromide(CTAB) and sodium oleate(SO) has been studied by spectrophotometry. The results show that for ASTP system with a certain ratio of CTAB to SO the volume of the upper phase decreased and that of the lower phase increased with increase of MIT added, while the distribution ratio K d and single extraction yield Y of MIT in two phases remained approximately constant.
The distribution of mitomycin (MIT) for injection in aqueous surfactant two phases (ASTP), consisted of cetyltrimethylammonium bromide (CTAB) and sodium oleate (SO) has been studied by spectrophotometry. The results show that for ASTP system with a certain ratio of CTAB to SO the volume of the upper phase decreased and that of the lower phase increased with increase of MIT added, while the distribution ratio K d and single extraction yield Y of MIT in two years remaining approximately constant.