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目的探讨依达拉奉联合氯吡格雷治疗急性脑梗死的临床疗效。方法回顾性分析120例急性脑梗死患者,随机分为观察组和对照组,各60例。在常规治疗的基础上,观察组给予依达拉奉联合氯吡格雷治疗,对照组给予氯吡格雷口服治疗。比较两组患者的临床疗效和神经功能缺损评分。结果治疗14 d后,观察组总有效率为90.0%明显高于对照组的70.0%(P<0.05);观察组神经功能缺损平均评分明显低于对照组(P<0.05)。结论依达拉奉联合氯吡格雷治疗急性脑梗死疗效显著,能有效促进神经功能恢复,值得在临床上广泛应用。
Objective To investigate the clinical efficacy of edaravone and clopidogrel in the treatment of acute cerebral infarction. Methods A retrospective analysis of 120 patients with acute cerebral infarction, were randomly divided into observation group and control group, 60 cases each. On the basis of routine treatment, the observation group was given edaravone combined with clopidogrel, and the control group was treated with clopidogrel orally. The clinical efficacy and neurological deficit scores were compared between the two groups. Results After 14 days of treatment, the total effective rate in the observation group was 90.0%, which was significantly higher than that in the control group (P <0.05). The average score of neurological deficit in the observation group was significantly lower than that in the control group (P <0.05). Conclusion Edaravone combined with clopidogrel treatment of acute cerebral infarction significant effect, can effectively promote the recovery of nerve function, it is widely used in clinical.