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将57例不能切除的原发性肝癌(简称肝癌)患者分为2组。1组26例,行肝动脉结扎加化疗栓塞。2组31例,在肝动脉结扎加化疗栓塞的同时经门静脉置入全埋入式药物输注装置(简称化疗泵),术后行门静脉灌注化疗。全部病例均随访1a以上。2组的肿瘤部分缓解率显著高于1组(P<0.025);2组的1a生存率也高于1组,接近显著水平(x2=3.37,x20.05(1)=3.84)。提示肝动脉结扎加化疗栓塞和门静脉灌注化疗是治疗不能切除肝癌的较好方法。
Fifty-seven patients with unresectable primary liver cancer (hepatocellular carcinoma) were divided into two groups. A group of 26 patients underwent hepatic artery ligation plus chemoembolization. Thirty-one patients in two groups were treated with hepatic artery ligation and chemoembolization, and a full-buried drug infusion device (abbreviated as chemotherapy pump) was placed through the portal vein. Portal vein infusion chemotherapy was performed postoperatively. All cases were followed up more than 1a. The partial remission rate was significantly higher in the 2 groups than in the 1 group (P<0.025); the 1a survival rate in the 2 groups was also higher than that in the 1 group, which was close to significant levels (x2=3.37, x20.05(1)=3 .84). It is suggested that hepatic artery ligation plus chemoembolization and portal vein chemotherapy are the better methods for the treatment of unresectable liver cancer.