链球菌超抗原在多种链球菌感染导致的疾病中发挥着重要作用。随着研究的深入,对链球菌的认识也取得了新的突破。文中对当前研究证实的链球菌超抗原成员及其结构特征、致病机制、表达调控进行了综述,并展望其在肿瘤治疗中的意义。 Streptococcus superantigens play an important role in many diseases caused by streptococcal infections. With the deepening of the research, new breakthroughs have been made in understanding of Streptococcus. In this paper, the members of Streptococcus superantigens confirmed by current research and their structural features, pathogenesis and expression regulation are reviewed, and their significance in the treatment of cancer is prospected.