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血清结合珠蛋白(Haptoglobin简称Hp)是血清α_2区球蛋白中的一种糖蛋白。1938年两名法国人(Polonovski,M和Jayle,M)最先提出了结合珠蛋白的概念1955年Smithese、O用淀粉凝胶电泳技术首次发现人血清Hp有三种主要的电泳图谱。从而引起了学术界的广泛重视。几十年来对Hp的研究不断深入,Hp的亚型化分,定量分析;Hp的肽链结构以及决定肽链合成的基因结构;Hp的遗传控制,进化意义;Hp的生理生化性质以及与疾病的相关性等诸方面研究均取得了很大进展。Barbara、H、
Serum haptoglobin (Haptoglobin referred to as Hp) is a glycoprotein in serum α_2 globulin. In 1938, two Frenchmen (Polonovski, M and Jayle, M) first proposed the concept of haptoglobin. In 1955, Smithese, O, discovered three major electrophoretic profiles of human serum Hp by starch gel electrophoresis. Which has aroused widespread academic attention. The research of Hp has been deepened for decades, the subtyping and quantitative analysis of Hp; the structure of Hp peptide and the gene structure of peptide synthesis; the genetic control and evolutionary significance of Hp; the physiological and biochemical properties of Hp, The correlation and other aspects of research have made great progress. Barbara, H,