睡眠呼吸暂停综合征(SAS)是一种睡眠期疾病,由于夜间睡眠期间出现反复多次呼吸暂停从而造成严重低氧血症和高碳酸血症,引起肺动脉高压甚至肺心病,近年来研究认为,SAS 与心血管疾病关系密切,可导致继发性高血压,心肌缺血,心律失常,心力衰竭,甚至夜间猝死,早期治疗可以延缓并发症的发生,改善预后。1 病因及临床表现SAS 病因未明,可能与只在睡眠发生的脑干功能异常有关,本病可见于多种疾患,如慢性阻塞性肺疾患,肺心病,肥胖低通气综合征,肢端肥大症,下颌畸形,扁桃体肥大,鼻腔息肉,脑干梗塞等临床症状除原发病的表现外,可有入睡时 Sleep apnea syndrome (SAS) is a sleep-stage disease, due to repeated episodes of sleep apnea during nighttime resulting in severe hypoxemia and hypercapnia, causing pulmonary hypertension and pulmonary heart disease, recent studies suggest that, SAS and cardiovascular disease are closely related, can lead to secondary hypertension, myocardial ischemia, arrhythmia, heart failure, and even sudden death at night, early treatment can delay the occurrence of complications and improve prognosis. 1 etiology and clinical manifestations of SAS etiology is not yet known, may be associated with dysfunction of brain stem only occurs during sleep, the disease can be found in a variety of disorders, such as chronic obstructive pulmonary disease, pulmonary heart disease, obesity, hypoventilation syndrome, acromegaly , Mandibular deformity, tonsil hypertrophy, nasal polyps, brain stem infarction and other clinical symptoms in addition to the performance of the primary disease, may have to sleep