36例原发性高血压(>5年)患者在降压治疗开始前或降压治疗停止4周后,收缩压持续>20.0kPa 或者舒张压持续>12.5kPa。根据超声心动图测值计算缩短分数、左室肌重量和收缩末室壁应力。各例均有左室肥厚,即室间隔和左室壁的厚度≥12mm,左室肌重量>正常均值+2×标准差。根据收缩末室壁应力分为两组。A 组15例收缩末室壁应力<正常均值-2×标准差。B 组21例收缩末室壁应力在正常范围(正常均值±2×标准差)之内。AB 两组的年龄(55±9对51±11岁)、性别(男性14/15对18/21)、收缩压(20.1±1.7对21.0±1.2kPa)、舒张压(13.0±1.2对12.8±1.6kPa)和左室肌重量(331±66对318±73g)均无显 Thirty-six patients with essential hypertension (> 5 years) had systolic blood pressure> 20.0 kPa or diastolic blood pressure> 12.5 kPa 4 weeks after initiation of antihypertensive therapy or 4 weeks after antihypertensive treatment was discontinued. Shortening fraction, left ventricular muscle mass, and end-systolic wall stress were calculated from echocardiographic measurements. Each case had left ventricular hypertrophy, that is, the thickness of ventricular septum and left ventricular wall ≥ 12mm, left ventricular muscle weight> normal average + 2 × standard deviation. According to the end-systolic wall stress is divided into two groups. A group of 15 cases of end-systolic wall stress