目的观察沙眼衣原体泌尿生殖道感染的迁延性并分析其可能的原因。方法随访了经正规治疗后的沙眼衣原体感染者223例,观察其治愈情况。结果经正规治疗后,仍有22.87%的病人呈阳性检出,更改方案治疗,一年时仍有40.48%的病人呈顽固抵抗,其中以女性为多。结论沙眼农原体泌尿生殖道感染过程隐匿、迁延、持续,这是多种原因造成的,比如机体自身的免疫力、沙眼衣原体的感染特点以及耐药基因等。 Objective To observe the persistence of genitourinary tract infection of Chlamydia trachomatis and analyze its possible causes. Methods Totally 223 cases of Chlamydia trachomatis infection after regular treatment were followed up and the cure was observed. Results After regular treatment, there were still 22.87% of patients were positive detection, change the program of treatment, a year still 40.48% of the patients were stubbornly resistant, of which more women. Conclusion Trachoma agalactia genitourinary tract infection process concealment, prolongation, sustained, which is caused by many reasons, such as the body’s own immunity, Chlamydia trachomatis infection characteristics and resistance genes.