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目的分析老年女性冠心病患者并发抑郁症的发病情况和临床特点。方法于2012年1月~2014年3月,抽取100例老年女性冠心病患者作为此次研究的对象,应用汉密尔顿抑郁量表(HAMD)进行评估,根据评估结果分为冠心病合并抑郁症组(观察组)和冠心病未合并抑郁症组(对照组),并对比分析冠心病合并抑郁症的临床症状、发生原因,以及两组患者的动态心电图监测结果和死亡情况。结果老年女性冠心病合并抑郁症的发病率为54%,其临床症状主要为抑郁情绪、睡眠障碍、兴趣减退等。动态心电图监测结果显示,与对照组相比,观察组的室性心律失常、房性心律失常以及缺血性ST-T波段改变等发生率均明显更高(P<0.05)。随访发现,与对照组相比,观察组的两年内死亡率明显更高(P<0.05)。结论老年女性冠心病患者并发抑郁症的概率较高,且多表现出抑郁症的核心症状,其预后较差,临床上应对该疾病患者进行积极有效的治疗。
Objective To analyze the incidence and clinical features of depression in elderly women with coronary heart disease. Methods From January 2012 to March 2014, 100 elderly women with coronary heart disease were enrolled in this study. Patients were assessed by Hamilton Depression Rating Scale (HAMD), and were divided into two groups according to the results: coronary heart disease complicated with depression group Observation group) and non-combined depression group (control group). The clinical symptoms and causes of coronary heart disease complicated with depression as well as the results and mortality of ambulatory electrocardiogram monitoring and death in two groups were compared. Results The incidence of coronary heart disease with depression in elderly women was 54%. The main clinical symptoms were depression, sleep disturbance, decreased interest and so on. Holter monitoring showed that the incidence of ventricular arrhythmia, atrial arrhythmia and ischemic ST-T band in the observation group were significantly higher than those in the control group (P <0.05). Follow-up found that, compared with the control group, the observation group two-year mortality was significantly higher (P <0.05). Conclusion The elderly women with coronary heart disease complicated by depression have a higher probability of depression, and more show the core symptoms of depression, the prognosis is poor, clinical treatment of the disease in patients with active and effective treatment.