本文探讨了固态膜汞离子选择电极的制备方法。将ＨｇＮＯ_３·Ｈ_２Ｏ溶于沸水中，加硫酸生成硫酸汞。称取干燥硫酸亚汞０．５５ｇ，压成固体膜（１００００ｋｇ／ｃｍ~２５ｍｉｎ），内充电解质为液汞，其它按ＢＰ（１９８８）附录ⅧＥ项下方法制备。该电极在醋酸盐缓冲液中符合Ｎｅｒｎｓｔ方程，在０．０２～０．２０ｍｍｏｌ／Ｌ［Ｈｇ~（＋＋）］范围内，线性关系良好（ｒ＝０．９９９），浓度响应斜率约４５ｍＶ，响应时间小于３０ｓ。它被用于汞盐电位滴定法测定氨苄青霉素，ＲＳＤ为０．２７％，而紫外分光光度法ＲＳＤ为０．９２％（ｎ＝５）。 This article discusses the preparation of solid-state membrane mercury ion selective electrode. The HgNO_3 · H_2O dissolved in boiling water, add sulfuric acid to generate mercury sulfate. Weigh dry 0.55g of mercury sulfate, pressed into a solid film (10000kg / cm ~ 25min), filled with electrolyte liquid mercury, the other by BP (1988) Appendix Ⅷ E prepared under the method. The electrode was fitted to the Nernst equation in acetate buffer with a good linearity (r = 0.999) in the range of 0.02-0.20 mmol / L [Hg ~ (++)] with a slope of concentration response of about 45 mV, Response time is less than 30s. It was used for the determination of ampicillin by the mercury salt potentiometric titration with a RSD of 0.27%, while the RSD of UV spectrophotometry was 0.92% (n = 5).