轮状病毒 (ＲＶ)Ａ、Ｂ、Ｃ组均可感染人类 ,Ａ组是婴幼儿、年幼动物的重要致病原。它可以在小肠粘膜分化上皮内复制 ,导致急性、自限性腹泻 ,其发病率和严重程度居秋冬季腹泻的首位。全球每年约有 1 4亿人发生ＲＶ引起的腹泻 ,并导致大约 80万儿童死亡。近年来 ,各国科学工作 Rotavirus (RV) can infect humans in groups A, B and C, and group A is an important causative agent of infants and young animals. It replicates intraepithelially in small intestine mucosa, resulting in acute, self-limiting diarrhea, with its incidence and severity ranking first in autumn and winter diarrhea. About 1.4 billion people globally worldwide experience RV-induced diarrhea and cause the deaths of some 800,000 children. In recent years, various countries have scientifically worked