合成了１６个６氯１环丙基７（１哌嗪基）１，４二氢４氧代喹啉３羧酸及其类似物，并测定了抗菌活性，结果表明，化合物１１Ｃａ及１１Ｃｃ对金葡菌１５的活性是环丙沙星的４倍，对大肠杆菌２２和绿脓杆菌２９的活性与环丙沙星相当 Synthesis of 16 6  chloro  1  cyclopropyl  7  (1  piperazinyl)  1, 4  2  4  dihydroquinoline  3  carboxylic acid and its analogs, and measured Antibacterial activity, the results showed that compounds 11Ca and 11Cc of Staphylococcus aureus 15 activity ciprofloxacin 4 times the activity of E. coli 22 and Pseudomonas aeruginosa 29 and ciprofloxacin quite