就蛋白而言去乙酰化酶(sirtuin)是令人喜欢的,而且因它们与衰老和年龄相关疾病相关联而受到人们的广泛关注。作为去乙酰化酶的来源,线粒体,也因在健康和疾病中的作用而闻名于世。来自美国哈佛医学院的Marcia Haigis和她的团队从事基础研究,提出了一个较为深刻的问题荘细胞中,哪些蛋白与去乙酰化酶进行交谈? Sirtuins are pleasing to the protein and are receiving much attention because of their association with aging and age-related diseases. As a source of sirtuins, mitochondria are also known for their role in health and disease. Marcia Haigis from Harvard Medical School in the United States and her team engaged in basic research and raised a rather profound question. Which cells in the cell are talking to the sirtuin?