内脂素是一种来源于内脏脂肪的新脂肪因子,它可能在心脑血管疾病、糖尿病、代谢综合征和肾脏疾病等动脉粥样硬化性疾病中发挥重要作用。内皮细胞损伤是动脉粥样硬化病灶形成的始动环节。近年来大量研究证实内脂素对血管内皮功能的影响非常复杂,且可能与炎症、氧化应激或血脂紊乱等机制有关。 Flutin, a novel adipokine derived from visceral fat, may play an important role in atherosclerotic diseases such as cardiovascular and cerebrovascular diseases, diabetes mellitus, metabolic syndrome and kidney disease. Endothelial cell damage is the first step in the formation of atherosclerotic lesions. In recent years, a large number of studies have confirmed that visfatin on vascular endothelial function is very complex and may be related to inflammation, oxidative stress or dyslipidemia mechanisms.