1984年9月26日,我县某地误将皮上划痕卡介苗与旧结核菌素混合后,于前臂内侧皮内注射,进行“结素试验”,致使192名学生发生严重反应。其中男生120例,女生72例,年龄11～17岁,经7个多月全部康复。结果观察一、局部反应混合误种后,全部出现硬结和脓肿,30.7％出现水泡。脓肿破溃最早于种后5天,最迟135天,多集中在两周内(65.7％),溃疡最大直径为4cm,29周后全部愈合。未发现疤痕疙瘩。 September 26, 1984, a county in our county mistakenly labeled scratch BCG mixed with the old tuberculin, the medial forearm intradermal injection, the “knot test”, resulting in a serious reaction of 192 students. Among them there are 120 boys and 72 girls, aged 11-17 years old. All of them recovered after more than 7 months. Results observed a local reaction mixed misdemeanor, all appear induration and abscess, blistering 30.7%. Abscesses ruptured the earliest 5 days after breeding, no later than 135 days, mostly concentrated in two weeks (65.7%), ulcer maximum diameter of 4cm, 29 weeks after the full healing. No keloids found.