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目的 :分析北京市东城区2001—2011年甲状腺癌发病的变化趋势。方法 :利用2001—2011年北京市东城区居民甲状腺癌的发病资料,按性别和年龄计算甲状腺癌的发病率,采用世界标准人口计算标化率,采用对数直线回归法估算发病率的年度变化百分比(annual percent change,APC)。结果 :2001—2011年,北京市东城区居民甲状腺癌累计发病563例,其中男性125例,女性438例,男女性别比为1∶3.50。甲状腺癌发病率由2001年的2.69/10万上升至2011年的14.29/10万,增长431.23%;标化率从1.69/10万上升至9.33/10万,增长452.07%。甲状腺癌发病率随着年龄的增长而上升,25~64岁各年龄组甲状腺癌发病率呈现显著上升的趋势,男性发病高峰出现在70~74岁组,女性发病高峰出现在45~49岁组和75~79岁组。男、女性甲状腺癌发病率的APC分别为16.88%和15.60%。结论 :北京市东城区2001—2011年甲状腺癌发病率上升较快,需要深入分析甲状腺癌高发的原因,并针对性地采取预防措施。
Objective: To analyze the trend of thyroid cancer incidence in Dongcheng District of Beijing from 2001 to 2011. Methods: According to the incidence of thyroid cancer in Dongcheng District of Beijing from 2001 to 2011, the incidence of thyroid cancer was calculated by gender and age. The standardization rate of the world population was used to calculate the standardization rate. The annual change of incidence was estimated by logarithmic linear regression Annual percent change (APC). Results: From 2001 to 2011, 563 cases of thyroid cancer were found in Dongcheng District, Beijing. There were 125 males and 438 females with a sex ratio of 1: 3.50. The incidence of thyroid cancer increased from 2.69 / 100,000 in 2001 to 14.29 / 100,000 in 2011, an increase of 431.23%. The standardization rate rose from 1.69 / 100,000 to 9.33 / 100,000, an increase of 452.07%. The incidence of thyroid cancer increased with age, the incidence of thyroid cancer in all age groups of 25-64 years showed a significant upward trend, the peak incidence of men appeared in the group of 70-74 years, and the peak incidence of women appeared in the group of 45-49 years And 75 to 79 years old group. The incidences of thyroid cancer in men and women were 16.88% and 15.60%, respectively. Conclusion: The incidence of thyroid cancer in Dongcheng District of Beijing from 2001 to 2011 increased rapidly. The causes of high incidence of thyroid cancer need to be analyzed in depth and the preventive measures should be taken accordingly.