多器官功能障碍(MODS)及衰竭(MOF)是当代创伤外科和危重病急救医学的重大课题,MODS发生率为6％～7％,死亡率为70％,甚至高达80％以上,4个以上器官受损几乎100％死亡。MODS病因极其复杂,目前认为多与严重创伤、休克、严重感染、输血输液不当有关。 1 判断MODS的标准 原发致病因素必须是急性的,而继发性损伤大都发生于远隔部位的组织器官,其来势凶猛,病死率很高;致病与发生MODS,必须有一定的间隔时间(>24 Multiple organ dysfunction (MODS) and failure (MOF) are major topics in contemporary traumatic surgery and critical care medicine. The incidence of MODS is 6% -7%, the mortality rate is 70%, even up to 80%, and more than 4 Organ damage is almost 100% fatal. The cause of MODS is extremely complex, and is currently considered to be associated with severe trauma, shock, severe infections, and inappropriate blood transfusion. 1 to determine the standard primary disease risk factors MODS must be acute, and secondary to injury mostly occurred in the distant parts of the tissues and organs, its ferocious, high mortality; pathogenic and the occurrence of MODS, there must be a certain interval Time (> 24