白芍过敏一例报告

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患者用陈氏,女,54岁,枣庄市郊区公社陈庄大队。1979年6月27日初诊。门诊号:127165。喘憋,全身起荨麻疹半天。昨天因腹疼腹泻,大便脓血,里急后重,轻度寒热,去市中区医院就诊。查大便常规:脓血便,脓细胞(+++),白细胞(++),红血球(+++),吞噬细胞(+).诊断为菌痢。给予芍药汤加减两剂治之。昨晚服第一剂,有轻度胸闷咳喘、皮肤搔痒感。今天上午服第二剂,半小时后,渐觉呼吸困难,憋喘胸闷,身起荨麻疹,搔痒身热,烦躁不安,急来我院就诊。既往有胃炎及慢性支气管炎病史。考虑为过敏性反应。给予福美松10mg静脉推注,朴尔敏4mg日三次,维生素C200mg日三次。半小时后缓解,两小时后明显好转。次日因仍腹痛便,脓血,里急后重,来我科诊治,复予芍药汤加厚朴、山楂、葛根治之。服药半小时后,又出现上述过敏反应,经激素、抗过敏药物治疗后方安。这时,才引起我们注意。对照两院处方,仅有厚朴一味之差。对处方中十二味药物进行筛选:先将白芍全部检出,服其他十一味,腹痛腹泻明显好转,且无过敏反应。又给加入小剂量白芍3g,则又出现喘憋、荨麻疹。服抗过敏药后,痊愈。 The patients were Chen and female, 54 years old, and the Chenzhuang Brigade, a commune in the outskirts of Zaozhuang City. Newly diagnosed on June 27, 1979. Outpatient number: 127165. Asthmatic, systemic urticaria half a day. Yesterday, due to abdominal pain and diarrhea, bloody stools, tenesmus, mild cold and heat, go to the city hospital for treatment. Check the stool routine: pus and blood, purulent cells (+++), white blood cells (++), red blood cells (+++), and phagocytic cells (+). Diagnosis is bacillary dysentery. Give peony decoction plus two treatments. The first dose last night served with mild chest tightness, cough, and itching. After taking the second dose this morning, half an hour later, she felt difficulty in breathing, chest tightness, urticaria, pruritus, irritability and urgency. He came to our hospital urgently. Previous history of gastritis and chronic bronchitis. Consider an allergic reaction. Fumoxetene 10mg intravenous injection, Pyrmin 4mg three times a day, vitamin C 200mg three times a day. He eased after half an hour and improved significantly after two hours. The next day because of still abdominal pain, pus and blood, tenesmus, to our department of diagnosis and treatment, re-treatment of wolfberry soup thickened Park, Hawthorn, Gegen governance. About half an hour after taking the drug, the above-mentioned allergic reaction occurred, and the patient was treated with hormones and anti-allergic drugs. At this time, we caught our attention. Compared with the two hospital prescriptions, only Ho-Pak is blindly. The screening of the twelve taste drugs in the prescription: first detect all the white peony, take the other 11 tastes, abdominal pain, diarrhea was significantly improved, and no allergic reaction. After giving a small dose of white peony 3g, asthma and urticaria appear again. After taking anti-allergic drugs, healed.
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