在甲苯中,以ZnBr_2为催化剂、4-二甲氨基吡啶为碱,通过N-Boc取代的炔基胺类化合物的环化反应合成了5位取代的2-噁唑烷酮类化合物。考察了催化剂种类、碱、温度等对反应的影响,在优化条件下以良好的产率得到了一系列目标产物。 In toluene, 5-substituted 2-oxazolidinone compounds were synthesized by the cyclization of N-Boc-substituted alkynyl amines with ZnBr 2 as catalyst and 4-dimethylaminopyridine as base. The effect of catalyst type, alkali and temperature on the reaction was investigated. A series of target products were obtained with good yield under the optimal conditions.