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甲胎蛋白(AFP)作为肝脏肿瘤的特异性标志物,是诊断原发性肝癌的重要指标,然而在我国约有30%~40%的原发性肝癌患者血清AFP为阴性[1]。本文回顾性分析AFP阴性与AFP阳性原发性肝癌患者的临床特点及影响其预后的因素,以期增加对AFP阴性原发性肝癌的认识。
AFP as a specific marker of liver tumors is an important indicator of the diagnosis of primary liver cancer, however, about 30% to 40% of the patients with primary liver cancer in our country serum AFP is negative [1]. This article retrospectively analyzed the clinical features of AFP-negative and AFP-positive primary hepatocellular carcinoma patients and their prognostic factors in order to increase awareness of AFP-negative primary liver cancer.