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目的观察以三补化结法为核心治法的辨证组方治疗煤工尘肺患者的疗效。方法将118例煤工尘肺贰期患者按年龄随机分为观察组(68例)和对照组(50例),对照组给予常规对症治疗,观察组在常规治疗的基础上给予三补化结法治疗,疗程180d,治疗前后分别评价患者临床症状和体征改善情况、6min步行试验(6MWT)、血气、肺功能情况。结果经过180d治疗后,观察组咳喘、胸憋、咳痰、易感冒等症状明显改善(P<0.05),有效率明显高于对照组(P<0.05);观察组的6MWT距离(P<0.05)、PaO2和SaO2均明显提高,且优于对照组(P<0.05),差异均具有统计学意义。肺功能指标有好转的趋势。结论以三补化结法为核心治法的中医药综合疗法,明显缓解咳嗽、咳痰、胸憋、易感冒等临床症状,提高煤工尘肺患者活动耐量及血氧分压,并在一定程度上改善肺功能,值得在临床中推广及应用。
Objective To observe the effect of syndrome differentiation and syndrome differentiation treating coal worker’s pneumoconiosis patients with the three-supplementing and knot-knot as the core method. Methods A total of 118 patients with stage II pneumoconiosis were divided into observation group (68 cases) and control group (50 cases) randomly. The control group was given conventional symptomatic treatment. The observation group was given three supplementation methods Treatment, treatment 180d, before and after treatment were evaluated in patients with clinical symptoms and signs of improvement, 6min walk test (6MWT), blood gas, pulmonary function. Results After 180 days of treatment, the symptoms such as cough, chest and suffocation, expectoration and flu in the observation group were significantly improved (P <0.05), and the effective rate was significantly higher in the observation group than in the control group (P <0.05) 0.05), PaO2 and SaO2 were significantly increased, and better than the control group (P <0.05), the differences were statistically significant. Lung function indicators have improved trend. Conclusions The traditional Chinese medicine combined therapy with triple-supplementing therapy as the core treatment method can obviously relieve the clinical symptoms such as cough, expectoration, chest-stuffing, and flu-prone, and improve the activity of patients with pneumoconiosis and partial pressure of blood oxygen. To a certain extent On the improvement of lung function, it is worth in the clinical promotion and application.