论文部分内容阅读
目的探讨射频消融(radiofrequency ablation,RFA)联合经皮椎体成形(percutaneous vertebroplasty,PVP)治疗脊柱转移瘤的临床疗效。方法回顾性分析2012年6月至2016年10月于中国医学科学院肿瘤医院接受RFA+PVP治疗且资料完整26例(27个椎体)。VAS评分比较患者疼痛缓解、X线片比较椎体前缘高度恢复,采用配对t检验进行统计学分析。结果术后平均随访11.8(1~33)个月,疼痛缓解满意,有效率为92%,优良率为87%。手术前后进行VAS评分分别为(5.73±2.55)分、(2.58±1.84)分(P<0.05)。椎体前缘高度术前(24.34±5.68)mm,术后(32.23±5.71)mm,与术前相比差异有统计学意义(P<0.05)。结论 RFA联合PVP治疗脊柱转移瘤可获得良好的疼痛缓解,改善患者生活质量,疗效确切。
Objective To investigate the clinical efficacy of radiofrequency ablation (RFA) combined with percutaneous vertebroplasty (PVP) in the treatment of spinal metastases. Methods Retrospective analysis from June 2012 to October 2016 at the Cancer Hospital of Chinese Academy of Medical Sciences received RFA + PVP treatment and complete data in 26 cases (27 vertebral bodies). VAS score patients with pain relief, X-ray comparison of vertebral height recovery, the use of paired t-test for statistical analysis. Results The average follow-up was 11.8 (1-3 months) postoperatively. Pain relief was satisfactory with an effective rate of 92% and an excellent and good rate of 87%. VAS scores before and after surgery were (5.73 ± 2.55) and (2.58 ± 1.84) points, respectively (P <0.05). The height of anterior vertebral body was (24.34 ± 5.68) mm preoperatively and (32.23 ± 5.71) mm postoperatively, with significant difference compared with that before operation (P <0.05). Conclusion RFA combined with PVP treatment of spinal metastases can obtain good pain relief, improve patient quality of life, the exact effect.