尿液PH值筛查孕妇无症状菌尿的价值

来源 :国外医学.妇产科学分册 | 被引量 : 0次 | 上传用户:heyzol
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妊娠期无症状菌尿的发生率为2~10%。如不治疗,20~40%患者会发生急性肾盂肾炎。本前瞻性研究旨在探讨通过尿液pH改变本身或与其他快速筛查检验配合是否可查出孕妇无症状菌尿。自510例产前初诊孕妇收集干净中段尿液。在收集后10分钟内一部分尿用作试剂纸带式分析,测定尿液pH值、亚硝酸盐类以及白细胞酯酶活性。剩余的尿在4小时内送微生物学实验室,分别接种到羊血琼脂和Mac Conkey琼脂,前者在含5~8%CO_2的环境下、后者在大气环境下培养。采用非配对、双尾独立样本t检验进行统计学分析,显著性定在P≤0.05。共查出无症状菌尿24例,阳性率为4.7%。最常见的细菌为大肠杆菌(占71%)。无感染者尿液pH值分布频度与感染者相似,无感染者和感染者的尿液pH值众数是6.0(分别为32%和58%,两者 The incidence of asymptomatic bacteriuria during pregnancy is 2 to 10%. If not treated, 20 to 40% of patients develop acute pyelonephritis. This prospective study aims to investigate whether asymptomatic bacteriuria in pregnant women can be detected by changing urine pH itself or in combination with other rapid screening tests. A total of 510 prenatal pregnant women collected clean urine. A portion of the urine was used as a reagent strip test within 10 minutes of collection to determine urinary pH, nitrite, and leukocyte esterase activity. The remaining urine was sent to the microbiology laboratory within 4 hours and inoculated into sheep blood agar and Mac Conkey agar, respectively. The former was cultured in the atmosphere with 5 to 8% CO 2 and the latter in the atmosphere. Unpaired, two-tailed independent sample t-test for statistical analysis, significant set at P ≤ 0.05. A total of 24 cases of asymptomatic bacteriuria were detected, the positive rate was 4.7%. The most common bacteria is Escherichia coli (71%). The urinary pH of uninfected people was distributed at a similar frequency to that of those infected, with urine pH modalities of 6.0 (32% and 58%, respectively) for both non-infected and infected persons
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