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生长抑素(十四肽)是Brazeau在1974年从50万头羊的下丘脑抽提液中发现的,经过分离,纯化得到了生长抑素的纯品并测定了一级结构,发现它对生长激素(GH)的分泌有显著的抑制作用。随着研究工作的深入,利用放射免疫测定和免疫组织化学技术,证明生长抑素分布于整个中枢神经系统以及胰脏和胃肠道。在大白鼠中,大约占生长抑素总量的25％存在于大脑,70％存在于胃肠道,5％存在于胰脏。由于生长抑素的这种双重分布以及它广泛的生理功能,不少学者建议,像这
Somatostatin (tetradecapeptide) was discovered by Brazaau in 1974 from the hypothalamus extracts of 500,000 sheep. After isolation, pure somatostatin was purified and the primary structure was determined and found to be The secretion of hormone (GH) has a significant inhibitory effect. With the in-depth research work, radioimmunoassay and immunohistochemical techniques have been used to demonstrate that somatostatin is distributed throughout the central nervous system and the pancreas and gastrointestinal tract. In rats, about 25% of total somatostatin is present in the brain, 70% in the gastrointestinal tract, and 5% in the pancreas. Due to this dual distribution of somatostatin and its wide range of physiological functions, many scholars have suggested that like this