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目的了解江苏省某地农村居民高三酰甘油腰围表型(hypertriglyceridemic waist phenotype,HTWP)的流行现状,并探讨其主要危险因素。方法采用横断面研究方法,于2012年10-11月对江苏省句容市各镇多阶段随机抽出的5 626名农村居民开展腰围与血清三酰甘油(TG)的测量与实验室检测,并开展问卷调查,利用t检验、方差分析等分析不同表型组特征差异,并采用非条件logistic回归模型筛选HTWP的独立危险因素。结果共有741名(13.17%)农村居民患有HTWP,在调整了年龄、性别、婚姻状况等混杂因素后,采用logistic回归模型分析出体力劳动职业类型(OR=1.360,CI:1.128~1.638,P=0.001),超重与肥胖(OR=3.247,CI:2.888~3.650,P<0.001),高血压病(OR=1.826,CI:1.529~2.181,P<0.001)以及高胆固醇血症(OR=1.815,CI:1.408~2.340,P<0.001)为HTWP发病的独立危险因素。结论 2012年江苏省句容市农村居民高三酰甘油腰围表型具有较高的流行率,其主要的独立危险因素包括体力劳动职业类型、超重与肥胖、高血压病以及高胆固醇血症,应加强对HTWP这一表型以及其影响因素的控制,同时应关注HTWP导致的其他慢性病。
Objective To investigate the epidemiological status of hypertriglyceridemic waist phenotype (HTWP) among rural residents in a certain area of Jiangsu Province and to explore its main risk factors. Methods A cross-sectional study was conducted to measure and measure the waist circumference and serum triglyceride (TG) of 5 626 rural residents randomly selected from each of the towns in Jurong, Jiangsu Province from October to November 2012 A questionnaire survey was conducted. T-test and analysis of variance (ANOVA) were used to analyze the differences of characteristics of different phenotype groups. The non-conditional logistic regression model was used to screen independent risk factors of HTWP. Results A total of 741 rural residents (13.17%) had HTWP. Logistic regression model was used to analyze the labor force occupational type (OR = 1.360, CI: 1.128-1.638, P (OR = 3.247, CI: 2.888-3.650, P <0.001), hypertension (OR = 1.826, CI: 1.529-2.181, P <0.001) and hypercholesterolemia , CI: 1.408 ~ 2.340, P <0.001) were independent risk factors of HTWP. Conclusion The prevalence of hypertriglyceridemia in rural residents in Jurong City, Jiangsu Province in 2012 was high. The main independent risk factors include occupational manual labor, overweight and obesity, hypertension and hypercholesterolemia, and should be strengthened The HTWP phenotype and its control factors, should also pay attention to other chronic diseases caused by HTWP.