硒预防克山病和大剂量维生素C 静脉注射治疗急型重症克山病取得显著疗效。膳食中缺乏维生素C 可引起动物组织脂质过氧化作用增强,脂质过氧化物的累积,并损害生物膜的结构和功能。大量维生素C 静脉注射对大鼠心肌脂质过氧化作用的影响,至今未见报道。本实验通过测定用西安粮、克山病病区 Selenium prevention Keshan disease and large doses of intravenous vitamin C treatment of severe acute Keshan disease achieved significant results. The lack of vitamin C in the diet can cause increased lipid peroxidation in animal tissues, accumulation of lipid peroxides, and impair the structure and function of biofilms. The effect of a large amount of vitamin C intravenous injection on myocardial lipid peroxidation in rats has not been reported so far. This experiment was conducted through the determination of Xi’an Food and Keshan disease area.