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为了考察磷酸钠口服清肠液(Ⅰ号)进行肠道准备的效果及安全性,选择了1995年6月至1996年3月间门诊及住院病人需作大肠镜检查者108例,以传统的口服洗肠液(Ⅱ号)为对照,随机分组,盲法给药,通过问卷调查对二者的耐受性、味道、不良反应及清洁效果等进行对比。结果显示Ⅰ号与Ⅱ号相比,患者可接受率分别为87.5%与69.2%,乐于饮用者分别为32.2%与15.4%,差异有显著性(P<0.05)。提示前者易于耐受,味道较好,因此,清肠效果必然满意。末发现严重不良反应及血化学改变,血渗透压改变在正常范围内,说明Ⅰ号液为一有效而安全的口服清肠剂。
In order to investigate the efficacy and safety of oral sodium phosphate clear bowel preparation (Ⅰ) for bowel preparation, we selected 108 outpatients and inpatients for colonoscopy from June 1995 to March 1996, Washing intestinal juice (Ⅱ) as a control, randomized, blindly administered by questionnaire on the tolerance, taste, adverse reactions and cleaning effects were compared. The results showed that the acceptability rates of patients Ⅰ and Ⅱ were 87.5% and 69.2%, respectively, and 32.2% and 15.4% respectively. There was significant difference (P <0.05). Tip is easy to tolerate the former, the taste is better, therefore, intestine bowel effect inevitably satisfied. Found no serious side effects and blood chemistry changes, changes in blood osmolality within the normal range, indicating fluid No. 1 is an effective and safe oral enema.