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[目的]探讨三维适形放疗治疗原发性肝癌的临床疗效。[方法]对进行三维适形放射治疗的46例原发性肝癌患者的临床资料进行回顾性分析,并与38例单纯接受导管动脉化学性栓塞术的原发性肝癌患者进行比较。[结果]观察组的近期有效率为86.96%,对照组的近期有效率为57.89%,观察组的有效率显著高于对照组,差别有统计学意义(P﹤0.05)。观察组1、2、3年生存率分别为82%,61.5%,23%;对照组1、2、3年生存率分别为72.5%,48.5%,8%。两组的生存率差异有统计学意义(χ2=5.87,P=0.032﹤0.05)。[结论]采用三维适形放射治疗方法治疗原发性肝癌具有良好的疗效,值得临床推广。
[Objective] To investigate the clinical efficacy of three-dimensional conformal radiotherapy in the treatment of primary liver cancer. [Methods] The clinical data of 46 patients with primary liver cancer undergoing three-dimensional conformal radiotherapy were retrospectively analyzed and compared with 38 patients with primary liver cancer who underwent chemical arterial embolization alone. [Results] The effective rate in the observation group was 86.96%, and the effective rate in the control group was 57.89%. The effective rate in the observation group was significantly higher than that in the control group (P <0.05). The 1-year, 2-year and 3-year survival rates in the observation group were 82%, 61.5% and 23%, respectively. The 1, 2 and 3-year survival rates in the control group were 72.5%, 48.5% and 8%, respectively. There was significant difference in survival between the two groups (χ2 = 5.87, P = 0.032 <0.05). [Conclusion] Three-dimensional conformal radiotherapy for the treatment of primary liver cancer has good curative effect and deserves clinical promotion.