病毒感染和免疫缺损(ID)间病因上的关连是一主要问题。涉及这些缺损的机理主要为假设性并取决于病毒感染的类型:急性,持续性或先天性。急性病毒感染:在很多急性病毒感染时发现对回忆性抗原有暂时的变应性消失。这些感染包括麻疹,风疹,流感,腮腺炎,水痘和急性肝炎。在很多这些病人中正常T细胞有轻度缺损,但病毒感染很少引起巨噬细胞功能障碍。其它机理认为淋巴细胞产物的负反馈可能有较大重要性,如抑制细胞和可溶因子或淋巴细胞毒性抗体。在其他轻度缺损中以淋巴细胞在体外对植物血凝素 The causal link between virus infection and immunodeficiency (ID) is a major issue. The mechanisms involved in these deficits are largely hypothetical and depend on the type of viral infection: acute, persistent or congenital. Acute virus infection: A transient allergic recall of recall antigen disappears in many acute viral infections. These infections include measles, rubella, flu, mumps, chickenpox and acute hepatitis. In many of these patients, normal T cells have mild defects but viral infections rarely cause macrophage dysfunction. Other mechanisms that the negative feedback of lymphocyte products may have greater importance, such as inhibition of cells and soluble factors or lymphocyte cytotoxic antibodies. In other mild defects in lymphocytes in vitro against phytohemagglutinin