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Ｈｏｌｄｅｒ[1] 等 ( 1965 )报道了低剂量全身照射对多发性骨髓瘤患者的临床疗效。Ｊｏｈｎｓｏｎ[2 ] 等 ( 1967)首次将低剂量全身照射用于治疗非何杰金氏淋巴瘤 ,并肯定了其抗肿瘤效果。当时由于受理论水平的限制及放射医学界传统观念的束缚 ,低剂量辐射的抗肿瘤作用未得到
Holder [1] et al (1965) reported the clinical efficacy of low-dose whole body irradiation in patients with multiple myeloma. Johnson [2] et al (1967) first used low-dose whole-body irradiation for the treatment of non-Hodgkin’s lymphoma and confirmed its anti-tumor effect. At that time, due to the restriction of theoretical level and the traditional concept of radiation medicine, the anti-tumor effect of low-dose radiation was not obtained